Woo Jin Kim, D.D.S., Ph.D., Attorney at Patent Law.

• Research Assistant Professor

• School of Dentistry, Department of Molecular Genetics

• Epigenetic Regulation of Aged Skeletomuscular Regeneration Program

• Seoul National University

Dr. Woo Jin Kim holds both a Ph.D. in Molecular Genetics and a D.D.S. in Dental Medicine from Seoul National University. Additionally, he is a certified Attorney at Patent Law. With his diverse professional background, Dr. Kim is passionate about engaging in both dental medicine and molecular genetics research.

Since 2020, Dr. Kim has been serving as a Research Assistant Professor at the School of Dentistry at Seoul National University. In 2022, he joined Harvard Medical School and Brigham and Women's Hospital as a Postdoctoral Associate. His previous experiences include working as a Postdoctoral Associate at the School of Dentistry at Seoul National University and as an Attorney at Patent Law at the R&DB Foundation at SNU.

His research interests include the epigenetic regulation of skeletomuscular tissue, protein delivery systems, the genetic regulation of osteogenic differentiation through chromatin conformational changes, and genetic diseases of the skeletal system such as cleidocranial dysplasia and craniosynostosis. Dr. Kim is committed to advancing our understanding of these topics and contributing to the development of innovative treatments and technologies in the field.

First/Principle author Publications

• Kim, W. J., S. U. Rahman, Chung, S. H., Woo, K. M., Nanofibrous topography-driven altered responsiveness to Wnt5a mediates the three-dimensional polarization of odontoblasts. Materials Today Bio 2022. (IF = 10.76)

• Kim, W. J., Cho, Y.D., Ku, Y., Ryoo, H.M., The worldwide patent landscape of dental implant technology. Biomaterials Research 2022. (IF = 15.86)

• Kim, W. J., Kim, B. S., Kim, H. J., Cho, Y. D., Shin, H. L., Yoon, H. I., Lee, Y. S., Baek, J. H., Woo, K. M., Ryoo, H. M., Intratesticular Peptidyl Prolyl Isomerase 1 Protein Delivery Using Cationic Lipid Coated Fibroin Nanoparticle Complexes Rescues Male Infertility in Mice. ACS Nano 2020. (IF = 18.027)

• Kim, W. J, Shin, H. L., Kim, B. S., Kim, H. J., Ryoo, H. M., RUNX2-modifying enzymes: therapeutic targets for bone disease. Experimental & Molecular Medicine 2020, 52, 1178-1184. (IF=12.172)

• Cho, Y.W., Yun, J.H., Kwon, S.H., Eom, Y.J., Kim, W.J., Aggregate removal of particulate matter by selective protein-rich fraction of Moringa oleifera extract. Journal of Industrial Engineering Chemistry 2019, 81, 161-166. (IF=5.278)

• Kim, W. J., Kim, B. S., Cho, Y. D., Yoon, W. J., Baek, J. H., Woo, K. M., Ryoo, H. M., Fibroin particle-supported cationic lipid layers for highly efficient intracellular protein delivery. Biomaterials 2017, 122, 154-162. (IF=15.304)

• Kim, W. J., Islam, R., Kim, B. S., Cho, Y. D., Yoon, W. J., Baek, J. H., Woo, K. M., Ryoo, H. M., Direct Delivery of Recombinant Pin1 Protein Rescued Osteoblast Differentiation of Pin1-Deficient Cells. Journal of Cellular Physiology 2017, 232 (10), 2798-2805. (IF=6.513)

• Kim, B.S., Shin, H. R., Kim, H. J., Yoon, H. I., Cho, Y. D., Choi, K. Y., Choi, J. Y., Kim, W. J., Ryoo, H. M., Septal chondrocyte hypertrophy contributes to midface deformity in a mouse model of Apert syndrome. Scientific Reports 2021, 11, 7979 (IF=4.997)

Co-author Publications

• Kim, H. J.; Kim, W. J.; Ryoo, H. M., Post-Translational Regulations of Transcriptional Activity of RUNX2. Mol Cells 2020, 43 (2), 160-167.

• Cho, Y. D.; Kim, B. S.; Kim, W. J.; Kim, H. J.; Baek, J. H.; Woo, K. M.; Seol, Y. J.; Ku, Y.; Ryoo, H. M., Histone acetylation together with DNA demethylation empowers higher plasticity in adipocytes to differentiate into osteoblasts. Gene 2020, 733, 144274.

• Islam, R.; Yoon, H.; Kim, B. S.; Bae, H. S.; Shin, H. R.; Kim, W. J.; Yoon, W. J.; Lee, Y. S.; Woo, K. M.; Baek, J. H.; Ryoo, H. M., Blood-testis barrier integrity depends on Pin1 expression in Sertoli cells. Sci Rep 2017, 7 (1), 6977.

• Cho, Y. D.; Yoon, W. J.; Kim, W. J.; Woo, K. M.; Baek, J. H.; Lee, G.; Ku, Y.; van Wijnen, A. J.; Ryoo, H. M., Epigenetic modifications and canonical wingless/int-1 class (WNT) signaling enable trans-differentiation of nonosteogenic cells into osteoblasts. J Biol Chem 2014, 289 (29), 20120-8.

• Yoon, W. J.; Cho, Y. D.; Kim, W. J.; Bae, H. S.; Islam, R.; Woo, K. M.; Baek, J. H.; Bae, S. C.; Ryoo, H. M., Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 are crucial for fibroblast growth factor 2 (FGF2)-induced osteoblast differentiation. J Biol Chem 2014, 289 (13), 8828-38.

• Cho, Y. D.; Kim, W. J.; Yoon, W. J.; Woo, K. M.; Baek, J. H.; Lee, G.; Kim, G. S.; Ryoo, H. M., Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression. J Cell Physiol 2012, 227 (6), 2287-96.

Honors

• 2020 Best Young Scientist Award Korea-Japan-China, KBMR (Japan, Tokyo)

• 2019 Scientific Award, TCTBDR (China, Chengdu)

• 2019 Scientific Award with High Honor, KSBMR (Korea, Seoul)

• 2018 Joseph Lister Award (Basic Science), IADR (USA, Denver)

• 2017 Scholarship, D.D.S.-Ph.D Double Degree Program, NRF (Korea, Seoul)

Research Grant

• 2021~2026 Sei-Jong Fellowship Research Program, NRF (Korea)

• 2019~2022 Young Research Program, NRF (Korea)